hormone replacement therapy

noun

: the therapeutic use of hormones typically to increase diminished levels in the body : hormone therapy

The usual treatment for hypothyroidism is hormone replacement therapy.

—Kate Murphy

especially : the administration of estrogen often along with a synthetic progestin especially to ameliorate the symptoms of menopause and reduce the risk of postmenopausal osteoporosis

—abbreviation HRT

Examples of hormone replacement therapy in a Sentence

Recent Examples on the Web

In cases of clinically low testosterone, hormone replacement therapy may be introduced with careful monitoring for potential risks. —Ximena Araya-Fischel, Forbes.com, 26 June 2025

Violeta Acuna, a drag artist and activist, said access to hormone replacement therapy reduced her anxiety and depression. —Jo Yurcaba, NBC news, 20 June 2025

Ashton noted that hormone replacement therapy is not an automatic death sentence. —Harriette Cole, Flow Space, 3 June 2025

Most have competed on the team consistent with their gender assigned at birth, choosing to forgo hormone replacement therapy in order to qualify for competition, including nonbinary Team USA track and field athletes Nikki Hiltz and Raven Saunders. —Elizabeth Wolfe, CNN Money, 29 May 2025

Word History

First Known Use

1945, in the meaning defined above

Rhymes for hormone replacement therapy

• brachytherapy
• chemotherapy
• cryotherapy
• hydrotherapy
• hypnotherapy
• monotherapy
• phototherapy
• psychotherapy
• sclerotherapy
• immunotherapy
• pharmacotherapy
• physiotherapy

Medical Definition

hormone replacement therapy

noun

: the therapeutic use of hormones typically to increase diminished levels in the body : hormone therapy

The usual treatment for hypothyroidism is hormone replacement therapy.

—Kate Murphy

especially : the administration of estrogen often along with a synthetic progestin especially to ameliorate the symptoms of menopause and reduce the risk of postmenopausal osteoporosis

—abbreviation HRT