hormone replacement therapy

noun

: the therapeutic use of hormones typically to increase diminished levels in the body : hormone therapy

The usual treatment for hypothyroidism is hormone replacement therapy.

—Kate Murphy

especially : the administration of estrogen often along with a synthetic progestin especially to ameliorate the symptoms of menopause and reduce the risk of postmenopausal osteoporosis

—abbreviation HRT

Examples of hormone replacement therapy in a Sentence

Recent Examples on the Web

According to Caamano, women in menopause who are being treated with hormone replacement therapies and have thyroid conditions must be monitored vigorously. —Elizabeth Yuko, Flow Space, 28 Aug. 2025

In some cases, hormone replacement therapy (HRT) may also help. —Jennifer Jay Palumbo, Forbes.com, 25 Aug. 2025

From a physical standpoint, doctors recommend that any termination of hormone replacement therapy takes place gradually over three to six months, rather than cold turkey. —Candice Norwood, Them., 11 Aug. 2025

Health care may include the use of hormones to delay puberty in adolescents, behavioral health counseling to support and promote the gender identity with which a person aligns, and hormone replacement therapy. —Natalie Eilbert, jsonline.com, 5 Aug. 2025

Word History

First Known Use

1945, in the meaning defined above

Rhymes for hormone replacement therapy

• brachytherapy
• chemotherapy
• cryotherapy
• hydrotherapy
• hypnotherapy
• monotherapy
• phototherapy
• psychotherapy
• sclerotherapy
• immunotherapy
• pharmacotherapy
• physiotherapy

Medical Definition

hormone replacement therapy

noun

: the therapeutic use of hormones typically to increase diminished levels in the body : hormone therapy

The usual treatment for hypothyroidism is hormone replacement therapy.

—Kate Murphy

especially : the administration of estrogen often along with a synthetic progestin especially to ameliorate the symptoms of menopause and reduce the risk of postmenopausal osteoporosis

—abbreviation HRT