hormone replacement therapy

noun

: the therapeutic use of hormones typically to increase diminished levels in the body : hormone therapy

The usual treatment for hypothyroidism is hormone replacement therapy.

—Kate Murphy

especially : the administration of estrogen often along with a synthetic progestin especially to ameliorate the symptoms of menopause and reduce the risk of postmenopausal osteoporosis

—abbreviation HRT

Examples of hormone replacement therapy in a Sentence

Recent Examples on the Web

One in 5 women delayed or passed up menopause treatment due to financial concerns and only 26% have insurance coverage for hormone replacement therapy, according to a 2025 study from GoodRx. —Laura Trujillo, USA Today, 22 June 2026

The review found that liraglutide was better for health outcomes than hormone replacement therapy. —Angelica Stabile, FOXNews.com, 20 June 2026

The longer-term roadmap includes perimenopause monitoring, hormone replacement therapy calibration, and diagnostics for conditions like PCOS and endometriosis. —Lily Mae Lazarus, Fortune, 17 June 2026

For women, Svendsen says there is also power in combining GLP-1s with hormone replacement therapy. —Derek James, CBS News, 16 June 2026

Word History

First Known Use

1945, in the meaning defined above

Rhymes for hormone replacement therapy

• brachytherapy
• chemotherapy
• cryotherapy
• hydrotherapy
• hypnotherapy
• monotherapy
• phototherapy
• psychotherapy
• sclerotherapy
• immunotherapy
• pharmacotherapy
• physiotherapy

Medical Definition

hormone replacement therapy

noun

: the therapeutic use of hormones typically to increase diminished levels in the body : hormone therapy

The usual treatment for hypothyroidism is hormone replacement therapy.

—Kate Murphy

especially : the administration of estrogen often along with a synthetic progestin especially to ameliorate the symptoms of menopause and reduce the risk of postmenopausal osteoporosis

—abbreviation HRT